The Long-tailed weasel is the larger of the two weasels in Oregon, but smaller than the other member of the genus, the mink. Males are considerably larger than females. The head is flattened and somewhat triangular; the body and neck are elongate and almost cylindrical; the legs are short, and the tail is long. The summer pelage is brown dorsally; the venter is yellowish to orangish except for a white chin and sometimes one or more scattered brown spots. The tip of the tail is black. The pelage is molted twice annually. In the Cascade Range and eastward through the remainder of the state, the winter pelage often is white although in parts of the region some individuals may remain brown in winter. This species occurs throughout the state.
Long-tailed weasels are active throughout the year. Although they sometimes are considered to be nocturnal, they are often active during the daylight hours. Weasels can swim and climb but they mostly hunt on the ground. When snow is on the ground, they often seek prey by burrowing beneath the snow.