The Western spotted skunk is smaller and more weasel-like than the Striped skunk. The pelage is black with a somewhat pentagonal white patch between the eyes, a round white patch on each side of the head and four or six segmented white body stripes. This skunk is endowed with a muscle-encapsulated musk gland similar to those of the Striped skunk and so similarly, can eject musk from two papillae located under the tail. The odor of the musk is considered somewhat more pungent or acrid but is less spreading than that of the Striped skunk.
In Oregon, this skunk occurs throughout most of the state but it is believed not to occur in most of the Willamette Valley. It does not hibernate, but tends to be less active during periods of unusually cold weather. It is primarily nocturnal and highly secretive. Although equipped with a superb defense system, the Western spotted skunk tolerates considerable disturbance before resorting to the use of musk.